Transforming Targets Into Candidates
Designed to Add Certainty and Speed to Your Program With Small Molecule Drug Discovery Expertise + AI
Welcome to Logica, a groundbreaking collaboration between Charles River and Valo Health.
With decades of industry-leading drug discovery and data generation experience, deep artificial intelligence (AI) drug discovery expertise, plus a risk-sharing business model, we offer a novel, comprehensive drug discovery platform that aspires to enhance the predictability and success of your program.
Your benefits:
- Leading-edge AI/machine learning (ML) to accelerate your innovation
- Predictable outcomes through experimental expertise
- Human insights that drive expert decision-making
- Access to virtual and physical high-throughput hit finding capabilities (incl. DNA-encoded libraries)
- Speed, certainty, and shared risk to help you reach patients faster
Discover how Logica® can redefine your journey from
target to preclinical development.
Prioritizing Drug Discovery Predictability:
Know Your Budget, Get Your Candidate
We understand the challenges that come with small molecule drug discovery — the uncertainties, risks, and unpredictable outcomes. That’s why we’ve designed a revolutionary approach that centers on predictability, transparency, and reducing risk to expedite success.
No more hidden costs or unreliable timelines. With Logica, you receive a fixed budget up front, tied to key value-inflection points along the way. This fully managed, risk-sharing model aligns our success with yours, demonstrating our unwavering commitment to your drug discovery project’s outcome: our risk, your reward.
Target Biology Compound Candidate:
Single Partner, Shared Purpose
Logica believes in drug discovery technology and was designed to propel preclinical programs from conception to candidate nomination. We seamlessly fuse cutting-edge laboratory capabilities with AI-driven molecular design. Keeping human drug discovery expertise at the epicenter, we are positioned to expedite candidate selection with unprecedented accuracy.
The Power of Logica’s Deliverables
Our flexible offerings encompass three essential deliverables allowing you to engage with any or all phases of our integrated platform. You can enter or exit at any point in the process — use just one phase or combine sequential phases based on your specific needs:
Hit Identification
Rapid model builds and virtual screening bolstered via DEL or rapid HTS if needed
Lead Optimization
De-risking lead molecules with PK and in vivo target engagement studies
Candidate Delivery
Generates a high-quality, de-risked drug candidate asset; decision-ready for IND planning
Aim your lead design toward successful candidate selection: Our virtual advanceability assessment coupled with empirical measurements enables an astounding 90% success rate in generating viable and advanceable lead series.
Tap into hundreds of in vitro and in vivo models and thousands of computational predictive models, providing rapid advancement to candidate selection.
Amalgamate molecular design prowess and biological assay data into a closed loop discovery system, iteratively constructing high precision predictive models.
Scan a broader universe of actionable chemistry and rapidly iterate through billions of virtual molecules in each cycle to rank and deliver novel chemistries and results.
Embrace a Solution Beyond AI
Moving AI from promise to transformation requires native integration with drug discovery expertise and full-service small molecule drug discovery capabilities.
Our unique approach unites Charles River’s drug discovery and experimental prowess, Valo Health’s molecular design platform, and a visionary risk-sharing model in a holistic suite of services, ensuring the highest confidence in the success of your target → lead → candidate journey.